5 RESULTS
COMMENT This paper carries forward an emerging theme in the literature, which they reference, that Alzheimer’s disease is a network disease of the brain. By that I mean that the anatomy, or the space the disease occupies, conforms to what has been dubbed the brai
COMMENT This paper builds nicely on the realization that the spread of neurodegenerative diseases within the human brain is confined to specific, functionally defined networks. In the case of the behavioral variant of frontotemporal dementia, this involves the br
COMMENT I read the paper and enjoyed it. Staging of AD using PET with both ligands for amyloid and tau has appeared in previous papers, as acknowledged by the authors. This has most convincingly been done in subjects with dominantly inherited AD where the clinica
COMMENT This is a very interesting paper. One of the intriguing features of AD is the anatomy of the human brain that is vulnerable. I believe that a reasonable consensus is that it involves the hippocampus and the default mode network, which has been characteriz
COMMENT This is a very nice study that points ever more explicitly to the fact that selective vulnerability among brain networks is an important feature of AD. The brain’s default mode network (DMN) stands out in this regard and forces us to consider what it is a
